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If your local database has all of your changes, change your MobileMe settings in the MobileMe (or .Mac) preferences in System Preferences, then click the Reset button in the OmniFocus Sync preferences and click the MobileMe button again. Verify that you've got the right URL showing in the location field, and hit the sync button.

It won't be convenient to move just some of the changes you make in the new location back to the old location, just so you know...not impossible, but not convenient...