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Following the listed steps, neither the Return or Enter or spacebar activate the "Open" button. Esc doesn't click cancel, neither.

I have Enable Access for Assistive Devices selected in my Mac preferences, as well as "Tab selects links and form controls" in Omni's preferences.

Similar UI weirdness showed up in testing: command-comma to get Omni's prefs, tab to select "Show All" in its button bar, space to activate it but then tab no longer selects anything.