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you can't increase memory. not possible under os x. only photoshop is able to allocate a specific amount of memory steadyly. guess compress the database for removing old deleted entries would be a first step imho. but aside the ui needs some optimization to speed things up.

i am also suffering the same effects from time to time. especially when many apps are running and not much physical ram is left (on a pb 1,67 ghz with 1,5 gig ram)