[wilsonng]

I think OF is better suited for tasks. For general reference and FYI stuff, I put all of that into DevonThink Pro Office.

Then I put tasks with real deadlines into BusyCal/iCal.

I'd use PersonalBrain more for the higher elevations of focus.

I wished there was an all-in-one but I think having a variety of programs that are actually focused on one part of my GTD system serves me better.