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I've seen this (or something similar) occasionally when plugging and unplugging an external monitor that uses a substantially different color profile than the display on my Macbook, possibly combined with some fast user switching to a test account that doesn't have either display calibrated. I haven't seen any evidence that it is Omni's fault except to the degree that they chose an icon color where the color shift is more apparent...I'm not 100% sure, but I think I've even seen the blue icon in the dock when OmniFocus isn't running.