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I changed the growl settings (in the growl preferences pane in System Preferences) so that notifications for Available, Due Soon, and Overdue stay on my screen indefinitely, and that clicking on them notifies OmniFocus. I also changed to a display style (Crystal) that puts up smallish rectangles, sort of like little Post-It notes. Now as things become available for action (or require immediate action) I get a notification, and if it is something quick, I can do it and click on the OF icon in the notification to go directly to the item in OF and mark it off. I make extensive use of start dates/times and repeating actions and this works well for driving execution for me.