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OmniFocus 1.1 for the Mac has bonjour syncing now. The next version of the iPhone app will also have bonjour syncing. I don't have a firm date for that.

Bonjour will save some people from paying for MobileMe or another WebDAV service. However, not all of these issues will be moot at that point.

If you have OmniFocus on a desktop at home and a desktop at work, Bonjour syncing won't work (unless you've got some crazy networking wizardry beyond my knowledge). For bonjour syncing, you pick one of your Macs to keep the central database on. Each other mac or device has to be put on the same local network as that central mac at least occasionally in order to sync. If you use a web service, each mac or device could sync any time it has an internet connection.

Some people are also asking for a web app, so you could update your OmniFocus data from any computer with an internet connection, or maybe even a web-enabled phone. Bonjour doesn't address this either.