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How long does your OmniFocus database take to sync? How many clients do you have? How recently have they been synced? Are you using WebDAV or Bonjour? Have you tired contacting support for help? It's free for licensed users and you can reach them by email or phone.

I ask all this because my OmniFocus database rarely takes more than 5 seconds to sync over MobileMe on a Wi-Fi connection. I have two clients (a Mac and an iPhone), both are synced a couple times a day, and my database has around 2200 actions and 330 projects with a file size of about 500 KB (no attachments).

I know there are further syncing optimizations/fixes planned, but in my experience, OmniFocus as it is today has been pretty solid/quick with syncing. I have no complaints whatsoever in that area.