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Sorry the interface isn't more clear about what's happening!

OmniFocus can only sync your main database, but it can open alternate databases (such as its database backups). It sounds like you've accidentally started editing an alternate database rather than your main one—or at least that's what OmniFocus thinks.

If you command-click on the title of your window, OmniFocus will show you which database you're editing.

If this isn't enough to help you figure out where the problem is, don't hesitate to contact our Support Humans for help: omnifocus@omnigroup.com or 1-800-315-6664.