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I have not experienced kernel panics at all on my MacBook Pro or iMac although my MacBook Pro is a June 2007 model and I've been using OmniFocus since it was in beta. You might want to post the additional details of your setup (exact MBP model, operating system, version of OmniFocus, and anythig else you think is relevant). The only time I've had kernel panics I thought it was caused by MacSpeech's Dictate, but it appears to have been a hardware problem (Dictate makes fairly heavy use of the hardware so that may have just made it more likely to happen while it was running) as Apple replaced my one month old iMac with a new one in 2009 and I haven't had any since.

Did you change/upgrade your memory recently?