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I use the calendar to remind me to do things that need to be done at a specific time/place. These will usually be things that involve other people. For all the rest of the time, I look at OmniFocus and select tasks based on urgency and context. I don't make any attempt to plan out what I'm going to work on for the next week except to identify those things that I need to get done. About the closest I come to making a schedule is picking a bunch of things to do today, and often that will simply be to make sure I don't just choose to do nothing but the enjoyable options to the exclusion of tedious but necessary ones.

I guess it all boils down to:

Look at the calendar. If there's something you are supposed to do right now, do it. Otherwise, look at OmniFocus. Pick something to do, do it.

Repeat.