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Looks like the Remember the Milk folks have figured out a path to replace the reminder app with their app via a calDav integration. See http://blog.rememberthemilk.com/2011/10/we-taught-siri-to-add-tasks-to-remember-the-milk/ and http://techcrunch.com/2011/10/19/teach-siri-to-interact-with-rememberthemilk/

Could the same thing be done w/ Omnifocus?