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I checked out the RTM integration, and they did it by setting up a CALDAV calendar that intercepts one of the reminder lists. It's a very elegant setup I have to admit. My main Mac lost it's hard drive which has me in a hindered state right now too so I guess it looked even more elegant as it didn't require local scripting.

This is the closest I've come to moving away in some time. The biggest challenge I have in my workflow is capture, and Siri has that nailed.