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Something that's annoying and is probably a slight cpu suck is the constant iDisk syncing due to my OmniFocus file changing so often. Almost every time I look at the sidebar in Finder, it is downloading changes (and it's almost always OminFocus.ofocus).

Would setting the target directory to save the file to one of the non-synced folders help? Saving to 'Backup', 'Library', or something like that?

Hope that question makes sense and maybe someone has tried it.