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Thanks for the reply.

I was looking for the .lock-file in the location you specified but I had (unintentionally) moved the database to another location so I didn't find it. When a reboot didn't solve the problem I let it be. But the 10.5.2 update fixed it (or maybe it was the permission repair done before the update). Just moved the database back to the Application Support folder so that I will find it next time.