[whpalmer4]

So just to be clear, they don't ever display guides for their centers, only their edges? Is the snap-to-grid option turned on?

I've noticed that if there objects between the object I'm moving and the object I want to align with, the center line guide often doesn't appear. Whether that is intentional behavior or not, I do not know.

If you get this to happen again, and it happens even after quitting OmniFocus and reopening the file, you should send the file to Omni via Help->Send Feedback and see if they can track it down. There's an option to replace all text with gibberish if the document has confidential information.