Lost in space?
Deep in the weeds?
What Omnifocus needs is re-focusing.
It fails to support the ability to manage one's level of attention, because one of its most powerful capabilities, Perspectives, is shrunk down to a puny little pop-up window, which has about has much use as a used fast-food paper wrapper, and because you can't manage more than a handful of perspectives, nor can you use the software itself to manage the sequence and the timing of how you use perspectives.
URGENT RECOMMENDATION:
You need a full-blown perspectives management capability. You need the ability to have
200 perspectives! You need to be able to cluster perspectives into groupings and to be able to name those groupings. You need to have another layer in the data model that creates workflow actions. You need to tie workflow actions to perspectives and to perspective groups. You need to be able to open multiple perspectives simultaneously into set configurations on-screen, so that multiple perspective windows are
spatially distributed the same way across an iMac screen every time you open the grouping. You need to be able to integrate
SCHEDULED WORKFLOW with perspectives and perspective groupings.
You also need to have a higher level of reminder prompts (ie., higher than the actions currently provided), to review particular perspectives or sets of them and to remind you of what actions you need to take to process them.
Let's make Omnifocus more than just a garbage can model of GTD. (With apologies to James March, Michael D. Cohen, and Johan P. Olsen.
http://en.wikipedia.org/wiki/Garbage_Can_Model)