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You could copy the Omnifocus database to your USB thumbdrive.

From there you could double click the file to open it in OF, or if you wanted to full feature set to work, you could try an alias, or probably more likely to work a symbolic link created in the terminal.

After copying your OmniFocus file from ~/Library/Application Support/OmniFocus to your thumbdrive. Delete the copy in your Library folder, and then use a terminal command like this to create a symbolic link:

ln -s "~/Library/Application Support/OmniFocus/OmniFocus.ofocus" /Volumes/thumbdrive/OmniFocus.ofocus

You will need to change thumbdrive to the volume name of your USB storage.

On the other machine, just delete the OF database file, and run the same command.

You will NEED to quit OF before ejecting the drive, or you could lose data, or screw up OF with regard to its lock file.