A bit off topic answer following, but I really doubt Outlook will be scriptable for OF, although I could be wrong. Anyway:
I thought the same as you did when switching to Mac, but today I only use native programs; Mail, Address Book, iCal. To compensate for a few of Mail's shortcomings in mail handling, I use
Mail Tags and Mail Act-on. I have been connected to an MS Exchange server for nearly two years, and there is no doubt that Mail has had far fewer issues than Outlook users at work had during that time. I never regretted switching in other words.
For consolidating data: If you need to link info and see it in one place, there is Bento as a cheap, very ok solution. As for professional, large databases there is nothing matching Filemaker whereas a free form alternative is Devonthink (which I use myself). The latter works great with OF too, by the way.